IDENTIFICATION AND ANALYSIS OF SERPIN-FAMILY GENES BY HOMOLOGY AND SYNTENY ACROSS THE 12 SEQUENCED DROSOPHILID GENOMES

Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes

Abstract Background The Drosophila melanogaster genome contains 29 serpin genes, 12 as single transcripts and 17 within 6 gene clusters.Many of these serpins have a short knee length kurtis conserved "hinge" motif characteristic of active proteinase inhibitors.However, a substantial proportion (42%) lacks this motif and represents non-inhibitory se

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Sequence variation and immunogenicity of the Mycoplasma genitalium MgpB and MgpC adherence proteins during persistent infection of men with non-gonococcal urethritis.

Mycoplasma genitalium is a sexually transmitted bacterial pathogen that infects men and women.Antigenic variation of MgpB and MgpC, the immunodominant adherence proteins of M.genitalium, is thought to contribute to immune evasion and chronic infection.We wahl kmx investigated the evolution of mgpB and mgpC sequences in men with non-gonococcal ureth

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